SCHEMBL12092148

SCHEMBL12092148

CC(C)(C)OC(=O)NCCOCCOCCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 1/20 0.49
TDP1 Q9NUW8 1/20 0.47
IDO1 P14902 1/20 0.44
CA12 O43570 5/20 0.43
CA1 P00915 5/20 0.43
CA2 P00918 5/20 0.43
CA9 Q16790 5/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
SUCNR1 Q9BXA5 2/20 0.41
EPHX1 P07099 1/20 0.40
BCHE P06276 1/20 0.40
CNR2 P34972 1/20 0.40
ADRB2 P07550 1/20 0.39
HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25640010 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL7263734 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL436333 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL26032485 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL12238318 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL13699509 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL25257785 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL14671684 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL22939187 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL25639770 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250135043-A1 DUAL-TARGETING COMPOUND FOR FIBROBLAST ACTIVATION PROTEIN (FAP) AND INTEGRIN avB3, PREPARATION METHOD THEREFOR AND USE THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO., LTD. (CN) 2025-05-01 US claimed
US-11992536-B2 Dual-targeting compound and preparation method and application thereof YANTAI LANNACHENG BIOTECHNOLOGY CO., LTD. (CN) 2024-05-28 US claimed
US-20240131205-A1 DUAL-TARGETING COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO., LTD. (CN) 2024-04-25 US claimed
WO-2024067531-A1 DUAL-TARGETING COMPOUND AGAINST FIBROBLAST ACTIVATION PROTEIN FAP AND INTEGRIN αVβ3, AND PREPARATION METHOD THEREFOR AND USE THEREOF 烟台蓝纳成生物技术有限公司 2024-04-04 WO claimed
EP-4253402-A1 DUAL-TARGETING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF Yantai Lannacheng Biotechnology Co., Ltd. (CN) 2023-10-04 EP claimed
CN-116751259-A Fibroblast activation protein FAP and integrin alpha v β 3 Dual targeting compounds and methods of making the same 烟台蓝纳成生物技术有限公司 2023-09-15 CN claimed
WO-2023098920-A1 DUAL-TARGETING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 烟台蓝纳成生物技术有限公司 2023-06-08 WO claimed
CN-115505032-A Fibroblast activation protein FAP and integrin alpha v β 3 Dual-targeting compound and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2022-12-23 CN claimed
CN-115286697-B Dual-targeting compound and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2022-12-13 CN claimed
CN-115286697-A Dual-targeting compound and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2022-11-04 CN claimed
US-12637473-B2 MDM2 protein degraders REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-05-26 US disclosed
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US disclosed
EP-4734988-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF USE THEREOF The Board of Trustees of the Leland Stanford Junior University (US) 2026-05-06 EP disclosed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
US-12594275-B2 Immunophilin binding agents and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-07 US disclosed
US-8952147-B2 Conjugates, preparation thereof, and therapeutic use thereof SANOFI (FR) 2015-02-10 US disclosed
US-8952147-B2 Conjugates, preparation thereof, and therapeutic use thereof SANOFI (FR) 2015-02-10 US disclosed
US-20120225089-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-09-06 US disclosed
US-20120225089-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-09-06 US disclosed
US-7455855-B2 Delivering substance and drug delivery system using the same SANTEN PHARMACEUTICAL CO., LTD. (JP) 2008-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637473-B2 MDM2 protein degraders MDM2, TP53, TP53BP1 MEN1 1485/4885KMT2A 1892/4885GAA 1301/4885
US-20250135043-A1 DUAL-TARGETING COMPOUND FOR FIBROBLAST ACTIVATION PROTEIN (FAP) AND INTEGRIN avB3, PREPARATION METHOD THEREFOR AND USE THEREOF FAP, ITGAV, ITGB3 MEN1 1988/4885KMT2A 4235/4885GAA 264/4885
US-20240131205-A1 DUAL-TARGETING COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF ITGAV, ITGA2, ITGB2 MEN1 370/4885KMT2A 2352/4885GAA 224/4885
US-20120225089-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF ERG28, CARS1, FOLH1 MEN1 486/4885KMT2A 3995/4885GAA 213/4885
US-12594275-B2 Immunophilin binding agents and uses thereof CCR1, CCRL2, CCR3 MEN1 2070/4885KMT2A 4235/4885GAA 4139/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR MEN1 688/4885KMT2A 1938/4885GAA 4537/4885
US-11992536-B2 Dual-targeting compound and preparation method and application thereof ITGAV, ITGB1, ITGB2 MEN1 325/4885KMT2A 2465/4885GAA 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.