SCHEMBL436333

SCHEMBL436333

CC(C)(C)OC(=O)NCCOCCOCCOCCOCCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 1/20 0.49
TDP1 Q9NUW8 1/20 0.47
IDO1 P14902 1/20 0.44
CA12 O43570 5/20 0.43
CA1 P00915 5/20 0.43
CA2 P00918 5/20 0.43
CA9 Q16790 5/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
SUCNR1 Q9BXA5 2/20 0.41
EPHX1 P07099 1/20 0.40
BCHE P06276 1/20 0.40
CNR2 P34972 1/20 0.40
ADRB2 P07550 1/20 0.39
HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25640010 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL7263734 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL26032485 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL12238318 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL13699509 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL25257785 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL14671684 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL12092148 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL22939187 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1
SCHEMBL25639770 1.00 MEN1 (0.49) MEN1KMT2AGAATDP1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4227300-B1 TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO LTD (CN) 2026-01-28 EP claimed
CN-118206611-A Cell surface protein targeting compound and cell surface protein enrichment method 中国科学院大连化学物理研究所 2024-06-18 CN claimed
US-11975079-B2 Truncated Evans Blue modified fibroblast activation protein inhibitor, preparation method and application thereof YANTAI LANNACHENG BIOTECHNOLOGY CO., LTD. (CN) 2024-05-07 US claimed
US-20230390421-A1 TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD AND APPLICATION THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO., LTD. (CN) 2023-12-07 US claimed
EP-4227300-A1 TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Yantai Lannacheng Biotechnology Co., Ltd. (CN) 2023-08-16 EP claimed
US-20190352625-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2019-11-21 US claimed
US-10160960-B2 Mutants of cocaine esterase THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2018-12-25 US claimed
US-20160177277-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-06-23 US claimed
WO-2015021187-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2015-02-12 WO claimed
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US disclosed
CN-120590466-B Compound of targeted fibroblast activation protein and application thereof 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) 2026-05-12 CN disclosed
US-20260118357-A1 TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2026-04-30 US disclosed
EP-4073062-B1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2026-04-29 EP disclosed
EP-4733308-A1 FAP-TARGETING COMPOUND, AND RADIONUCLIDE-LABELED COMPLEX BASED THEREON, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2026-04-29 EP disclosed
US-20080213175-A1 Click chemistry-derived cyclic peptidomimetics as integrin markers SIEMENS MEDICAL SOLUTIONS USA, INC. 2008-09-04 US disclosed
US-7371585-B2 Membranes incorporating recognition moieties GENENCOR INTERNATIONAL, INC. (US) 2008-05-13 US disclosed
US-7371585-B2 Membranes incorporating recognition moieties GENENCOR INTERNATIONAL, INC. (US) 2008-05-13 US disclosed
WO-2008033557-A2 CLICK CHEMISTRY-DERIVED CYCLIC PEPTIDOMIMETICS AS INTEGRIN MARKERS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2008-03-20 WO disclosed
EP-1887359-A1 Methods for the identification of PI3K interacting molecules and for the purification of PI3K CELLZOME AG (DE) 2008-02-13 EP disclosed
WO-2008015013-A1 METHODS FOR THE IDENTIFICATION OF PI3K INTERACTING MOLECULES AND FOR THE PURIFICATION OF PI3K CELLZOME AG (DE) 2008-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080213175-A1 Click chemistry-derived cyclic peptidomimetics as integrin markers ITGB1, ITGAM, ITGB3 MEN1 787/4885KMT2A 4133/4885GAA 2452/4885
US-20230390421-A1 TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD AND APPLICATION THEREOF FIBP, FAP, ANPEP MEN1 808/4885KMT2A 3250/4885GAA 178/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR MEN1 688/4885KMT2A 1938/4885GAA 4537/4885
US-11975079-B2 Truncated Evans Blue modified fibroblast activation protein inhibitor, preparation method and application thereof FIBP, FAP, ANPEP MEN1 808/4885KMT2A 3250/4885GAA 178/4885
US-20260118357-A1 TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE BTD, FABP2, FABP3 MEN1 4433/4885KMT2A 3600/4885GAA 3294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.