Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056685 | 0.87 | TSHR (0.44) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL15317975 | 0.84 | — | — | |
| SCHEMBL8707 | 0.84 | — | — | |
| SCHEMBL10673601 | 0.84 | — | — | |
| SCHEMBL30353890 | 0.83 | TDP1 (0.41) | TSHRFDPSTDP1 | |
| Hydrochloric Acid SCHEMBL10594297 | 0.81 | TSHR (0.37) | TSHRFDPSTDP1 | |
| Hydrochloric Acid SCHEMBL10674883 | 0.81 | TSHR (0.37) | TSHRFDPSTDP1 | |
| SCHEMBL28243404 | 0.81 | TSHR (0.37) | TSHRFDPSTDP1 | |
| SCHEMBL25685120 | 0.81 | ALDH1A1 (0.35) | TDP1 | |
| SCHEMBL26045938 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804861-B1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE AS SYK INHIBITORS | GENOSCO (US) | 2018-02-28 | — | — | EP | disclosed |