Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65650 | 0.88 | TAAR1 (0.57) | TAAR1NR3C2GPR84GPR52HRH3 | |
| SCHEMBL29013833 | 0.86 | TAAR1 (0.55) | TAAR1NR3C2GPR84GPR52HRH3 | |
| SCHEMBL29807940 | 0.86 | TAAR1 (0.55) | TAAR1NR3C2GPR84ALDH1A1GPR52 | |
| SCHEMBL6083781 | 0.77 | TAAR1 (0.53) | TAAR1GPR84KDM4EALDH1A1GPR52 | |
| SCHEMBL348856 | 0.77 | CHRNA7 (0.57) | CYP1A2CYP2D6 | |
| SCHEMBL1299860 | 0.76 | TAAR1 (0.52) | TAAR1GPR84HRH3DAOMAOA | |
| SCHEMBL13680805 | 0.74 | EPHX2 (0.55) | CYP11B1CYP11B2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19258592 | 0.73 | MEN1 (0.43) | TAAR1CYP2D6GPR52MEN1KMT2A | |
| SCHEMBL8128782 | 0.73 | TAAR1 (0.57) | TAAR1NR3C2CYP11B1CYP11B2GPR84 | |
| SCHEMBL347894 | 0.72 | LOXL2 (0.50) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287449-A2 | SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)- IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME | Incyte Holdings Corporation (US) | 2018-02-28 | — | — | EP | disclosed |