Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373825 | 0.90 | MAOA (0.59) | MAOAMAOBKMT2ASMN1; SMN2CHRM3 | |
| SCHEMBL15775508 | 0.87 | MEN1 (0.50) | MAOAMAOBKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL15775507 | 0.87 | MEN1 (0.50) | MAOAMAOBKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL14166168 | 0.86 | KMT2A (0.44) | MAOAMAOBKMT2ACHRM3ALDH1A1 | |
| SCHEMBL15777839 | 0.86 | SMPD1 (0.55) | MAOAMAOBKMT2ASMN1; SMN2CHRM3 | |
| SCHEMBL20373866 | 0.86 | CHRM3 (0.62) | KMT2ASMN1; SMN2CHRM3RAB9ANPC1 | |
| SCHEMBL19984429 | 0.86 | CHRM3 (0.62) | KMT2ASMN1; SMN2CHRM3RAB9ANPC1 | |
| SCHEMBL19903853 | 0.86 | MAOB (0.56) | MAOAMAOBKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL15777842 | 0.86 | SMPD1 (0.55) | MAOAMAOBKMT2ASMN1; SMN2CHRM3 | |
| SCHEMBL16697221 | 0.86 | RAB9A (0.46) | MAOAMAOBKMT2ASMN1; SMN2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |