Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25918071 | 0.85 | CASP2 (0.44) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL19682981 | 0.85 | CASP2 (0.44) | CASP2KMT2AMEN1NAAAEPHX1 | |
| SCHEMBL24812535 | 0.85 | SMN1; SMN2 (0.51) | CASP2KMT2AMEN1NAAAEPHX1 | |
| SCHEMBL2603187 | 0.85 | SMN1; SMN2 (0.51) | CASP2KMT2AMEN1NAAAEPHX1 | |
| SCHEMBL16260385 | 0.83 | MEN1 (0.63) | CASP2KMT2AMEN1NAAAEPHX1 | |
| SCHEMBL9943126 | 0.83 | MEN1 (0.63) | CASP2KMT2AMEN1NAAAEPHX1 | |
| SCHEMBL18768810 | 0.83 | CASP2 (0.52) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL26382685 | 0.83 | CASP2 (0.52) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL18768806 | 0.83 | CASP2 (0.52) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL18768947 | 0.83 | CASP2 (0.52) | CASP2KMT2AMEN1NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092256-B1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2022-05-18 | — | — | EP | disclosed |
| EP-2935331-B1 | PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF | ABBVIE INC (US) | 2018-02-28 | — | — | EP | disclosed |