Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25918071 | 0.87 | CASP2 (0.44) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL19903903 | 0.85 | CASP2 (0.43) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL19957918 | 0.85 | PAOX (0.52) | CASP2KMT2AMEN1NAAASLC6A5 | |
| SCHEMBL19957980 | 0.85 | PAOX (0.52) | CASP2KMT2AMEN1NAAASLC6A5 | |
| SCHEMBL20634865 | 0.84 | CASP2 (0.46) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL22433524 | 0.81 | KMT2A (0.42) | CASP2KMT2AMEN1SLC6A5ALDH1A1 | |
| SCHEMBL20310079 | 0.80 | CASP2 (0.47) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL14077543 | 0.78 | MEN1 (0.71) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL14086343 | 0.78 | MEN1 (0.71) | CASP2KMT2AMEN1NAAAFAAH | |
| SCHEMBL13819835 | 0.77 | CASP2 (0.74) | CASP2KMT2AMEN1NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210489-A1 | COMPOUNDS | M3 BIOTECHNOLOGY, INC. (US) | 2017-12-07 | — | — | WO | disclosed |