Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493698 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL9493702 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL11414658 | 0.88 | ESR1 (0.46) | ALDH1A1HTTNPSR1LMNAPKM | |
| SCHEMBL11414654 | 0.88 | ESR1 (0.46) | ALDH1A1HTTNPSR1LMNAPKM | |
| SCHEMBL18771006 | 0.85 | TSHR (0.43) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL23458240 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL20179477 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL8670406 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL18618524 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL8670402 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1HTTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903172-B | Method for stereoselectively synthesizing (E) -tri-substituted olefin | 温州大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-110903172-A | Method for stereoselectively synthesizing (E) -tri-substituted olefin | 温州大学 | 2020-03-24 | — | — | CN | disclosed |
| EP-2651374-B1 | PROCESS FOR DYEING KERATIN FIBRES USING A DIRECT DYE BEARING A DISULFIDE/THIOL/PROTECTED THIOL FUNCTION AND WATER VAPOUR | L'ORÉAL (FR) | 2018-02-28 | — | — | EP | disclosed |