Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493698 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL19903965 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL11414658 | 0.88 | ESR1 (0.46) | ALDH1A1HTTNPSR1LMNAPKM | |
| SCHEMBL11414654 | 0.88 | ESR1 (0.46) | ALDH1A1HTTNPSR1LMNAPKM | |
| SCHEMBL18771006 | 0.85 | TSHR (0.43) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL23458240 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL20179477 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL8670406 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL18618524 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1HTTNPSR1LMNA | |
| SCHEMBL8670402 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1HTTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984055-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | Materia, Inc. (US) | 2016-02-17 | — | — | EP | claimed |
| WO-2014169080-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | MATERIA, INC. (US) | 2014-10-16 | — | — | WO | claimed |
| CN-110903172-B | Method for stereoselectively synthesizing (E) -tri-substituted olefin | 温州大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-109852444-B | Preparation method of gasoline octane number improver | 山东聚兴新材料科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-109852443-B | Gasoline octane number improver and preparation method thereof | 山东聚兴新材料科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-110903172-A | Method for stereoselectively synthesizing (E) -tri-substituted olefin | 温州大学 | 2020-03-24 | — | — | CN | disclosed |
| CN-109852444-A | A kind of preparation method of Gasoline octane number enhancer | 山东聚兴新材料科技有限公司 | 2019-06-07 | — | — | CN | disclosed |
| EP-2984055-B1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | MATERIA INC (US) | 2018-10-17 | — | — | EP | disclosed |
| US-9758445-B2 | Preparation of surfactants via cross-metathesis | MATERIA, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9663459-B2 | Preparation of surfactants via cross-metathesis | MATERIA, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160186094-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | MATERIA, INC. | 2016-06-30 | — | — | US | disclosed |
| WO-2014169055-A9 | CROSS METATHESIS OF POLY-BRANCHED POLY-OLEFINS | MATERIA, INC. (US) | 2015-09-24 | — | — | WO | disclosed |
| WO-2015126462-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | MATERIA, INC. (US) | 2015-08-27 | — | — | WO | disclosed |
| WO-2014169080-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | MATERIA, INC. (US) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014169055-A1 | CROSS METATHESIS OF POLY-BRANCHED POLY-OLEFINS | MATERIA, INC. (US) | 2014-10-16 | — | — | WO | disclosed |
| CN-101494999-A | Method for using organic compound | GIVAUDAN SA (CH) | 2009-07-29 | — | — | CN | disclosed |
| EP-0350069-B1 | METHOD FOR OXIDIZING UNSATURATED AROMATIC COMPOUNDS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4967009-A | REACTING UNSATURATED AROMATIC COMPOUNDS WITH AROMATIC IODOSYL COMPOUNDS TO YIELD AROMATIC ALDEHYDES OR KETONES | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0350069-A2 | Method for oxidizing unsaturated aromatic compounds | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-3946081-A | OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160186094-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | SMURF2, EPHX2, SMURF1 | ALDH1A1 1887/4885TDP1 3068/4885HTT 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.