Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25129348 | 0.81 | NOS3 (0.47) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL11881227 | 0.79 | CCR1 (0.37) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL18634102 | 0.78 | NOS2 (0.35) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL22279036 | 0.76 | BRD4 (0.33) | — | |
| SCHEMBL24466707 | 0.73 | NOS3 (0.41) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL23655447 | 0.73 | CCR1 (0.32) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL18391431 | 0.73 | CYP1A2 (0.32) | — | |
| SCHEMBL6626617 | 0.71 | ERN1 (0.46) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL29952796 | 0.71 | ERN1 (0.46) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL19415151 | 0.71 | CCR1 (0.33) | CCR1CCR5CCR8NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287459-A1 | PURINYL-N-HYDROXYL PYRIMIDINE FORMAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | Guizhou Bailing Enterprise Group Pharmaceutical Co., Ltd. (CN) | 2018-02-28 | — | — | EP | disclosed |