Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 14/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 10/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129025 | 0.93 | PDE3B (0.41) | PRMT1CARM1PDE3BPDE3APRMT6 | |
| SCHEMBL16129012 | 0.84 | S1PR1 (0.39) | PRMT1CARM1PDE3BPDE3APRMT6 | |
| SCHEMBL16129006 | 0.83 | S1PR1 (0.39) | PRMT1CARM1PDE3BPDE3APRMT6 | |
| SCHEMBL16128987 | 0.83 | S1PR1 (0.38) | PRMT1CARM1PDE3BPDE3APRMT6 | |
| SCHEMBL16128988 | 0.80 | XDH (0.44) | PRMT1CARM1PDE3BPDE3APRMT6 | |
| SCHEMBL16129009 | 0.79 | PDE3B (0.41) | PRMT1PDE3BPDE3APRMT6S1PR1 | |
| SCHEMBL16127550 | 0.77 | PRMT1 (0.36) | PRMT1CARM1PRMT6PRMT8S1PR1 | |
| SCHEMBL16129067 | 0.76 | PRMT1 (0.38) | PRMT1CARM1PRMT6PRMT8 | |
| SCHEMBL16204231 | 0.76 | PRMT1 (0.45) | PRMT1CARM1PRMT6PRMT8 | |
| SCHEMBL19904785 | 0.75 | AR (0.33) | PRMT1CARM1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970134-B1 | PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2018-02-28 | — | — | EP | disclosed |