Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.51 |
| ▸ | PLK1 | P53350 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905328 | 0.90 | SLC40A1 (0.53) | SLC40A1PLK1PSMD14L3MBTL1RAB9A | |
| SCHEMBL15328545 | 0.86 | SLC40A1 (0.52) | SLC40A1PLK1PSMD14L3MBTL1RAB9A | |
| SCHEMBL15328640 | 0.86 | SLC40A1 (0.52) | SLC40A1PLK1PSMD14L3MBTL1RAB9A | |
| SCHEMBL20415195 | 0.86 | L3MBTL1 (0.40) | SLC40A1PSMD14L3MBTL1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL29624025 | 0.85 | SLC40A1 (0.51) | SLC40A1PLK1PSMD14L3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL28552491 | 0.85 | SLC40A1 (0.51) | SLC40A1PLK1PSMD14L3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL28016091 | 0.85 | SLC40A1 (0.51) | SLC40A1PLK1PSMD14L3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL28016092 | 0.85 | SLC40A1 (0.51) | SLC40A1PLK1PSMD14L3MBTL1RAB9A | |
| SCHEMBL15343062 | 0.84 | SLC40A1 (0.54) | SLC40A1PLK1PSMD14L3MBTL1RAB9A | |
| SCHEMBL18317971 | 0.84 | SLC40A1 (0.50) | SLC40A1PLK1PSMD14L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057959-B1 | DNA-PK INHIBITORS | VERTEX PHARMA (US) | 2018-02-28 | — | — | EP | disclosed |