Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905519 | 0.98 | HRH3 (0.33) | HRH3SIGMAR1TAAR1KCNH2C5AR1 | |
| SCHEMBL28051311 | 0.81 | THRB (0.41) | CYP3A4CYP2D6THRATHRB | |
| SCHEMBL19905512 | 0.78 | HRH3 (0.37) | HRH3SIGMAR1TAAR1KCNH2C5AR1 | |
| SCHEMBL19905613 | 0.77 | CA2 (0.44) | — | |
| SCHEMBL19905531 | 0.76 | — | — | |
| SCHEMBL19905569 | 0.75 | KMT2A (0.32) | TAAR1KMT2A | |
| SCHEMBL19905640 | 0.74 | HSD17B10 (0.33) | ALDH1A1POLBKMT2A | |
| SCHEMBL6236000 | 0.72 | HRH1 (0.48) | SIGMAR1TAAR1TDP1HRH1HTR1A | |
| SCHEMBL11307101 | 0.72 | HDAC4 (0.38) | TDP1HTR1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11309712 | 0.72 | MEN1 (0.38) | ALDH1A1CYP1A2POLBCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079687-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO LTD (KR) | 2018-02-28 | — | — | EP | disclosed |