Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906119 | 0.86 | PTGDR2 (0.39) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906092 | 0.82 | PTGDR2 (0.48) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905978 | 0.82 | PTGDR2 (0.40) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906210 | 0.82 | PTGDR2 (0.42) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906090 | 0.82 | MEN1 (0.39) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906156 | 0.82 | KDM4E (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906180 | 0.81 | PTGDR2 (0.41) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906365 | 0.81 | NAMPT (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905806 | 0.81 | PTGDR2 (0.35) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905993 | 0.81 | PTGDR2 (0.35) | PTGDR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |