Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905957 | 0.86 | PTGDR2 (0.43) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906137 | 0.83 | PTGDR2 (0.39) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906412 | 0.82 | TP53 (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905892 | 0.82 | PTGDR2 (0.37) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905995 | 0.82 | EIF4EBP1 (0.36) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906104 | 0.82 | KDM4E (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906133 | 0.82 | KMO (0.39) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906361 | 0.82 | KDM4E (0.33) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906086 | 0.82 | KDM4E (0.39) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906046 | 0.82 | EIF4E (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |