Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906139 | 0.85 | PTGDR2 (0.43) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19017855 | 0.84 | PTGDR2 (0.52) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906049 | 0.83 | PTGDR2 (0.40) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906413 | 0.82 | MAPT (0.43) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905949 | 0.82 | PTGDR2 (0.43) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905957 | 0.82 | PTGDR2 (0.43) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905893 | 0.82 | PTGDR2 (0.41) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906210 | 0.82 | PTGDR2 (0.42) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905890 | 0.82 | PTGDR2 (0.42) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905978 | 0.82 | PTGDR2 (0.40) | PTGDR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |