Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905842 | 0.90 | DYRK1A (0.35) | HRH3TLR8GSK3BDYRK1A | |
| SCHEMBL15342164 | 0.80 | BRD4 (0.31) | GSK3BDYRK1A | |
| SCHEMBL15342573 | 0.80 | CYP3A4 (0.37) | GSK3BDYRK1A | |
| SCHEMBL19906039 | 0.78 | PPARD (0.33) | — | |
| SCHEMBL19906166 | 0.75 | KDM4E (0.40) | — | |
| SCHEMBL19905971 | 0.74 | SCD (0.34) | HRH3GSK3BDYRK1A | |
| SCHEMBL19905919 | 0.70 | MAPK11 (0.36) | GSK3BDYRK1ADRD4 | |
| SCHEMBL19905836 | 0.70 | JAK1 (0.37) | KCNH2 | |
| SCHEMBL19906223 | 0.69 | MCHR1 (0.41) | — | |
| SCHEMBL20030474 | 0.69 | USP2 (0.34) | KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |