Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.41 |
| ▸ | FLT3 | P36888 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906221 | 0.89 | MCHR1 (0.36) | MCHR1FLT3PRMT5 | |
| SCHEMBL19905836 | 0.87 | JAK1 (0.37) | MCHR1 | |
| SCHEMBL19905966 | 0.84 | JAK1 (0.36) | MCHR1CYP2D6 | |
| SCHEMBL19905942 | 0.84 | DRD2 (0.40) | — | |
| SCHEMBL19905832 | 0.84 | MCHR1 (0.40) | MCHR1 | |
| SCHEMBL15342629 | 0.83 | CYP3A4 (0.39) | MCHR1FLT3PRMT5 | |
| SCHEMBL19906198 | 0.82 | NPC1 (0.40) | MCHR1 | |
| SCHEMBL15342220 | 0.81 | MCHR1 (0.36) | MCHR1FLT3PRMT5 | |
| SCHEMBL19906248 | 0.81 | CNR1 (0.35) | MCHR1 | |
| SCHEMBL19905920 | 0.80 | KDM4E (0.36) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |