Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906047 | 0.92 | KDM4E (0.35) | MCHR1KDM4EBRD4CASP3SENP8 | |
| SCHEMBL19906102 | 0.81 | KDM4E (0.32) | KDM4ELMNA | |
| SCHEMBL15342248 | 0.81 | — | — | |
| SCHEMBL15342668 | 0.81 | CYP3A4 (0.35) | — | |
| SCHEMBL19906065 | 0.79 | SREBF2 (0.35) | SREBF2KDM4ELMNAMAPTATM | |
| SCHEMBL19905816 | 0.78 | KDM4E (0.35) | MCHR1KDM4EIDH1 | |
| SCHEMBL19906265 | 0.77 | KDM4E (0.35) | SREBF2KDM4ECASP3SENP8SENP7 | |
| SCHEMBL19905985 | 0.77 | KDM4E (0.35) | MCHR1KDM4EMAPTIDH1 | |
| SCHEMBL19906277 | 0.76 | PTGDR2 (0.37) | KDM4ENPC1RAB9A | |
| SCHEMBL19906076 | 0.75 | KDM4E (0.37) | MCHR1KDM4ELMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |