Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906269 | 0.82 | EIF4E (0.40) | MAPTKDM4ELMNATRPM8MAP4K4 | |
| SCHEMBL19906236 | 0.81 | PTGDR2 (0.38) | KDM4EMAP4K4KMT2AALDH1A1MEN1 | |
| SCHEMBL19906103 | 0.79 | MCHR1 (0.33) | SREBF2MAPTKDM4ELMNAATM | |
| SCHEMBL19905874 | 0.78 | PTGDR2 (0.35) | KDM4EKMT2AALDH1A1MEN1PTGDR2 | |
| SCHEMBL19906063 | 0.78 | CYP3A4 (0.39) | MAP4K4 | |
| SCHEMBL15341098 | 0.78 | CYP3A4 (0.39) | MAP4K4 | |
| SCHEMBL15340988 | 0.78 | CYP3A4 (0.33) | MAP4K4 | |
| SCHEMBL19905813 | 0.78 | PTGDR2 (0.33) | MAPTKDM4EKMT2AALDH1A1NPC1 | |
| SCHEMBL19906088 | 0.77 | KDM4E (0.42) | KDM4ELMNATRPM8KMT2AALDH1A1 | |
| SCHEMBL19905858 | 0.77 | USP2 (0.38) | KDM4ELMNAKMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |