Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 2/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906394 | 0.91 | GRM5 (0.36) | GRM5CPT1ACPT1B | |
| SCHEMBL19906108 | 0.90 | CPT1A (0.35) | GRM5CPT1ACPT1B | |
| SCHEMBL19906107 | 0.89 | CPT1A (0.32) | CPT1ACPT1B | |
| SCHEMBL19906136 | 0.89 | GRM5 (0.36) | GRM5SYKCPT1ACPT1B | |
| SCHEMBL19906318 | 0.85 | PPARD (0.37) | — | |
| SCHEMBL19906288 | 0.84 | CSF1R (0.35) | — | |
| SCHEMBL19905857 | 0.84 | HRH4 (0.34) | — | |
| SCHEMBL19906122 | 0.84 | KDM4C (0.34) | — | |
| SCHEMBL19906126 | 0.83 | KDM4E (0.33) | — | |
| SCHEMBL19906320 | 0.83 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |