Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905990 | 0.90 | GRM5 (0.39) | GRM5KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906111 | 0.89 | PTGER3 (0.38) | GRM5KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906135 | 0.89 | CHRM2 (0.35) | GRM5SYKCPT1ACPT1B | |
| SCHEMBL19905979 | 0.88 | KDM4E (0.33) | GRM5KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL15342608 | 0.84 | CYP3A4 (0.35) | GRM5SYK | |
| SCHEMBL15342201 | 0.83 | SYK (0.34) | GRM5SYK | |
| SCHEMBL19905896 | 0.83 | ALDH1A1 (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906287 | 0.82 | KDR (0.37) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906022 | 0.82 | PTGER3 (0.37) | GRM5KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19905858 | 0.82 | USP2 (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |