Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18432984 | 0.88 | TSHR (0.40) | TSHR | |
| SCHEMBL6575285 | 0.72 | — | — | |
| SCHEMBL2813297 | 0.72 | TSHR (0.30) | TSHR | |
| SCHEMBL7749465 | 0.71 | DNM1 (0.37) | TSHR | |
| SCHEMBL7059800 | 0.71 | — | — | |
| SCHEMBL3421351 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL18295813 | 0.70 | — | — | |
| Methylamine SCHEMBL15442036 | 0.70 | TSHR (0.37) | TSHR | |
| SCHEMBL246513 | 0.69 | TSHR (0.41) | TSHR | |
| SCHEMBL4945754 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890704-B1 | 2'-ETHYNYL NUCLEOSIDE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |