Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906202 | 0.83 | PTGER3 (0.40) | PTGER3USP2HTT | |
| SCHEMBL15342193 | 0.81 | CYP11B1 (0.33) | CYP11B1CYP11B2PTGER3IDH1F10 | |
| SCHEMBL15342601 | 0.81 | CYP3A4 (0.35) | CYP11B1CYP11B2PTGER3F10 | |
| SCHEMBL19906196 | 0.78 | PTGER3 (0.34) | PTGER3USP2HTT | |
| SCHEMBL19906003 | 0.78 | TRIM24 (0.41) | — | |
| SCHEMBL19905990 | 0.77 | GRM5 (0.39) | CYP11B1CYP11B2PTGER3 | |
| SCHEMBL15342199 | 0.76 | PTGER3 (0.35) | PTGER3IDH1 | |
| SCHEMBL15342604 | 0.76 | CYP3A4 (0.35) | PTGER3 | |
| SCHEMBL19906264 | 0.76 | PTGER3 (0.34) | PTGER3IDH1 | |
| SCHEMBL19906330 | 0.76 | KDM4E (0.33) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |