Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906196 | 0.90 | PTGER3 (0.34) | PTGER3KMOCPT1ACPT1BAPOBEC3A | |
| SCHEMBL19906111 | 0.88 | PTGER3 (0.38) | PTGER3CPT1ACPT1BKLKB1KDM4E | |
| SCHEMBL19906003 | 0.87 | TRIM24 (0.41) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906264 | 0.87 | PTGER3 (0.34) | PTGER3PDE3AKDM4EMEN1ALDH1A1 | |
| SCHEMBL19905989 | 0.84 | NSD2 (0.38) | ALDH1A1 | |
| SCHEMBL15342604 | 0.84 | CYP3A4 (0.35) | PTGER3PDE3BPDE3A | |
| SCHEMBL19905990 | 0.83 | GRM5 (0.39) | PTGER3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906215 | 0.83 | CYP11B1 (0.33) | PTGER3HTTUSP2 | |
| SCHEMBL19905979 | 0.83 | KDM4E (0.33) | PTGER3CPT1ACPT1BKDM4EMEN1 | |
| SCHEMBL15342199 | 0.83 | PTGER3 (0.35) | PTGER3APOBEC3AAPOBEC3GPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |