Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 4/20 | 0.31 |
| ▸ | HTR1D | P28221 | 4/20 | 0.31 |
| ▸ | HTR1B | P28222 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906263 | 0.90 | EIF4EBP1 (0.32) | PTGER3KDM4ELMNASMN1; SMN2 | |
| SCHEMBL19905918 | 0.88 | PTGDR2 (0.34) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906191 | 0.87 | GYS1 (0.35) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906202 | 0.87 | PTGER3 (0.40) | PTGER3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL15342600 | 0.84 | CYP3A4 (0.34) | — | |
| SCHEMBL15342196 | 0.83 | PTGER3 (0.30) | PTGER3 | |
| SCHEMBL19906127 | 0.83 | FABP4 (0.36) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906003 | 0.82 | TRIM24 (0.41) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19905862 | 0.80 | KDM4E (0.37) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906196 | 0.79 | PTGER3 (0.34) | PTGER3KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |