Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 8/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906268 | 0.93 | EIF4E (0.38) | EIF4EKDM4EPTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906137 | 0.91 | PTGDR2 (0.39) | EIF4EKDM4EPTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906366 | 0.91 | CTSA (0.34) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906369 | 0.90 | KDM4E (0.38) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906060 | 0.90 | KDM4E (0.38) | EIF4EKDM4EPTGDR2MEN1ALDH1A1 | |
| SCHEMBL19905873 | 0.88 | SHMT1 (0.32) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906236 | 0.88 | PTGDR2 (0.38) | EIF4EKDM4EPTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906291 | 0.87 | PTGDR2 (0.33) | EIF4EKDM4EPTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906288 | 0.87 | CSF1R (0.35) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906328 | 0.87 | PTGER1 (0.34) | EIF4EKDM4EPTGDR2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |