Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905916 | 0.83 | KDM4E (0.40) | KDM4EGFERALDH1A1LMNAMAPT | |
| SCHEMBL19906351 | 0.80 | PTGDR2 (0.41) | KDM4EALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL15332356 | 0.77 | CYP3A4 (0.38) | MEN1KMT2A | |
| SCHEMBL15526337 | 0.77 | CYP3A4 (0.38) | MEN1KMT2A | |
| SCHEMBL19906365 | 0.76 | NAMPT (0.38) | KDM4EALDH1A1HTTHPGDPOLB | |
| SCHEMBL15342297 | 0.75 | PSD (0.34) | MEN1KMT2AKIT | |
| SCHEMBL19906174 | 0.75 | NAMPT (0.36) | KDM4EGFERALDH1A1HPGDMEN1 | |
| SCHEMBL19906033 | 0.75 | KDM4E (0.37) | KDM4EGFERALDH1A1KMT2A | |
| SCHEMBL17547120 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1MAPTHTTHPGD | |
| SCHEMBL19906162 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |