Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906322 | 0.88 | CNR1 (0.38) | CNR1KDM4EPTGDR2KMT2AALDH1A1 | |
| SCHEMBL19906064 | 0.87 | KDM4E (0.41) | KDM4EPTGDR2KMT2AALDH1A1MEN1 | |
| SCHEMBL19905797 | 0.85 | EIF4E (0.39) | KDM4EPTGDR2KMT2AALDH1A1MEN1 | |
| SCHEMBL19906088 | 0.84 | KDM4E (0.42) | KDM4EPTGDR2KMT2AALDH1A1MEN1 | |
| SCHEMBL19905876 | 0.84 | PTGDR2 (0.42) | KDM4EPTGDR2KMT2AALDH1A1MEN1 | |
| SCHEMBL19905964 | 0.84 | PTGDR2 (0.37) | CNR1KDM4EPTGDR2KMT2AALDH1A1 | |
| SCHEMBL19906275 | 0.83 | PTGDR2 (0.37) | KDM4EPTGDR2KMT2AALDH1A1MEN1 | |
| SCHEMBL19906164 | 0.83 | DYRK1A (0.40) | KDM4EMAPT | |
| SCHEMBL19906090 | 0.83 | MEN1 (0.39) | KDM4EPTGDR2KMT2AALDH1A1MEN1 | |
| SCHEMBL19906236 | 0.82 | PTGDR2 (0.38) | KDM4EPTGDR2KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |