Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 5/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 3/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906060 | 0.89 | KDM4E (0.38) | KDM4EKMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906325 | 0.88 | CNR1 (0.44) | CNR1KDM4EKMT2APTGDR2MEN1 | |
| SCHEMBL19906061 | 0.87 | KDM4E (0.37) | KDM4EKMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906086 | 0.87 | KDM4E (0.39) | KDM4EKMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906044 | 0.85 | SHMT1 (0.38) | KDM4EKMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906157 | 0.85 | KDM4E (0.38) | KDM4EKMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906291 | 0.85 | PTGDR2 (0.33) | KDM4EKMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906369 | 0.84 | KDM4E (0.38) | KDM4EKMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906229 | 0.84 | EIF4E (0.36) | KDM4EKMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL19906120 | 0.84 | KDM4E (0.34) | KDM4EKMT2APTGDR2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |