Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20001736 | 0.85 | TSHR (0.53) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL3680977 | 0.84 | TSHR (0.57) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL27542565 | 0.79 | TSHR (0.47) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL11232229 | 0.79 | TSHR (0.59) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL94906 | 0.78 | TSHR (0.68) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL8965903 | 0.78 | TSHR (0.53) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL328805 | 0.78 | TSHR (0.57) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL964801 | 0.78 | TSHR (0.57) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL164047 | 0.77 | THRB (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL19998240 | 0.77 | TSHR (0.65) | TSHRTHRBALDH1A1USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735444-B1 | Lithographic printing plate precursor for newspaper printing and method for producing the same, and plate making method of lithographic printing plate | FUJIFILM CORP (JP) | 2018-02-28 | — | — | EP | disclosed |