Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767205 | 0.91 | MAPT (0.47) | MAPTNPC1RAB9AKDM4EGAA | |
| SCHEMBL123415 | 0.86 | MAPT (0.55) | MAPTNPC1RAB9AKDM4ETDP1 | |
| SCHEMBL20969623 | 0.82 | HRH3 (0.48) | MAPTNPC1RAB9AKDM4EGAA | |
| SCHEMBL20851318 | 0.79 | MAPT (0.58) | MAPTNPC1RAB9AKDM4EGAA | |
| SCHEMBL7308225 | 0.77 | KMT2A (0.67) | MAPTNPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL11649257 | 0.77 | LMNA (0.70) | MAPTGAATHRBRECQLTDP1 | |
| SCHEMBL7329813 | 0.77 | NQO1 (0.67) | MAPTNPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL3182331 | 0.77 | HPGD (0.66) | MAPTNPC1RAB9AKDM4ETHRB | |
| SCHEMBL2231003 | 0.77 | TSHR (0.50) | MAPTNPC1RAB9AKDM4ERECQL | |
| SCHEMBL28546493 | 0.77 | MAPT (0.61) | MAPTNPC1RAB9AGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941474-B1 | HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION | NITTO DENKO CORP (JP) | 2018-02-28 | — | — | EP | disclosed |