SCHEMBL19909112

SCHEMBL19909112

N#Cc1c(-n2c3cc(-c4ccccc4)ccc3c3ccc(-c4ccccc4)cc32)cc(-c2ccncc2)cc1-n1c2cc(-c3ccccc3)ccc2c2ccc(-c3ccccc3)cc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.42
ADORA2A P29274 1/20 0.42
IMPDH2 P12268 1/20 0.40
SQOR Q9Y6N5 1/20 0.40
NOTUM Q6P988 1/20 0.40
PRKACA P17612 1/20 0.39
CDK8 P49336 1/20 0.39
CLK2 P49760 1/20 0.39
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39
CDK9 P50750 1/20 0.39
CDK5 Q00535 1/20 0.39
PRKCQ Q04759 1/20 0.39
ROCK1 Q13464 1/20 0.39
DYRK1A Q13627 1/20 0.39
LRRK2 Q5S007 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
MKNK1 Q9BUB5 1/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909068 0.96 SQOR (0.40) ADORA1ADORA2AIMPDH2SQORNOTUM
SCHEMBL19908954 0.92 MEN1 (0.45) ADORA1ADORA2AIMPDH2SQORNOTUM
SCHEMBL19909503 0.90 AURKA (0.43) ADORA1ADORA2AGSK3AGSK3BROCK1
SCHEMBL19908908 0.90 FLT3 (0.40) GSK3AGSK3BLRRK2
SCHEMBL19909016 0.90 ADORA1 (0.42) ADORA1ADORA2AIMPDH2SQORNOTUM
SCHEMBL19908912 0.89 FLT3 (0.39) SQORPRKACACDK8CLK2GSK3A
SCHEMBL19909426 0.89 PIP4K2A (0.42) ADORA1ADORA2ASQORMEN1KMT2A
SCHEMBL19908964 0.89 SQOR (0.35) ADORA1ADORA2AIMPDH2SQORPRKACA
SCHEMBL19919702 0.89 SQOR (0.35) ADORA1ADORA2AIMPDH2SQORPRKACA
SCHEMBL19908876 0.89 SQOR (0.40) ADORA1ADORA2AIMPDH2SQORNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed