SCHEMBL19909426

SCHEMBL19909426

Cc1cccc(-c2ccc3c4ccc(-c5cccc(C)c5)cc4n(-c4cc(-c5ccncc5)cc(-n5c6cc(-c7cccc(C)c7)ccc6c6ccc(-c7cccc(C)c7)cc65)c4C#N)c3c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIP4K2A P48426 1/20 0.42
MAPK14 Q16539 2/20 0.41
KDM4A O75164 1/20 0.39
KDM5B Q9UGL1 1/20 0.39
GRIA2 P42262 1/20 0.38
GRIA4 P48058 1/20 0.38
CHEK1 O14757 2/20 0.37
CDK1 P06493 1/20 0.37
CDK4 P11802 1/20 0.37
CCNA2 P20248 1/20 0.37
CCND1 P24385 1/20 0.37
CDK2 P24941 1/20 0.37
CCND3 P30281 1/20 0.37
MAP4K4 O95819 1/20 0.36
AR P10275 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ALDH1A1 P00352 2/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913182 0.98 PIP4K2A (0.41) PIP4K2AMAPK14KDM4AKDM5BGRIA2
SCHEMBL19909422 0.96 PIP4K2A (0.40) PIP4K2AMAPK14KDM4AKDM5BGRIA2
SCHEMBL19909060 0.92 KDM5B (0.39) PIP4K2AKDM4AKDM5BCHEK1CDK1
SCHEMBL19909059 0.90 PIK3CA (0.37) CHEK1CDK1CDK2MAP4K4ALDH1A1
SCHEMBL19909112 0.89 ADORA1 (0.42) KDM4AKDM5BADORA2AADORA1MEN1
SCHEMBL19909420 0.89 MAPK14 (0.39) PIP4K2AMAPK14KDM4AKDM5BGRIA2
SCHEMBL19913181 0.89 ADORA1 (0.40) PIP4K2AMAPK14KDM4AKDM5BGRIA2
SCHEMBL20620029 0.89 CYP11B2 (0.44) PIP4K2AMAPK14KDM4AKDM5BCHEK1
SCHEMBL19913188 0.89 MAPK14 (0.38) PIP4K2AMAPK14KDM4AKDM5BCHEK1
SCHEMBL19909153 0.88 TDP1 (0.35) ALDH1A1ADORA1KDM4EMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 PIP4K2A 3805/4885MAPK14 2544/4885KDM4A 4544/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 PIP4K2A 4543/4885MAPK14 2787/4885KDM4A 3328/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 PIP4K2A 3805/4885MAPK14 2544/4885KDM4A 4544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.