SCHEMBL19909138

SCHEMBL19909138

Cc1ccc2c3ccccc3n(-c3cc(C#N)c(-c4cc(C)nc(C)c4)cc3-n3c4ccccc4c4ccc(C)cc43)c2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.37
KDM4E B2RXH2 6/20 0.36
ALDH1A1 P00352 5/20 0.36
GLA P06280 4/20 0.36
GAA P10253 3/20 0.36
HTT P42858 2/20 0.36
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HPGD P15428 4/20 0.34
HSD17B10 Q99714 3/20 0.34
MAPK1 P28482 2/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
CRHBP P24387 1/20 0.33
KMT2A Q03164 1/20 0.33
CRHR2 Q13324 1/20 0.33
IMPDH2 P12268 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909139 0.94 MAOA (0.34) GRM2KDM4EALDH1A1GLAGAA
SCHEMBL19913217 0.93 KDM4E (0.36) GRM2KDM4EALDH1A1GLAGAA
SCHEMBL22170397 0.93 KDM4E (0.36) GRM2KDM4EALDH1A1GLAGAA
SCHEMBL19919838 0.92 MAOA (0.34) GRM2KDM4EALDH1A1GLAGAA
SCHEMBL19919833 0.91 GRM2 (0.35) GRM2KDM4EALDH1A1GLAGAA
SCHEMBL19909334 0.90 PTGER4 (0.35) KDM4EALDH1A1GLACYP1A2CYP2C9
SCHEMBL22170373 0.90 ALDH1A1 (0.36) KDM4EALDH1A1GLAGAACYP1A2
SCHEMBL19919639 0.89 GRIN1 (0.33) GRM2KDM4EALDH1A1GLACYP1A2
SCHEMBL19913212 0.89 CYP1A2 (0.38) KDM4EALDH1A1GLACYP1A2CYP2C9
SCHEMBL22563563 0.88 GRM2 (0.37) GRM2KDM4EALDH1A1GLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed