Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19913161 | 0.98 | FLT3 (0.40) | CHEK1FLT3MAPKAPK2ALDH1A1MAPK14 | |
| SCHEMBL19919611 | 0.94 | FLT3 (0.42) | CHEK1FLT3MAPK14CSNK1A1CSNK1D | |
| SCHEMBL19908939 | 0.92 | MAPK14 (0.40) | CHEK1FLT3MAPKAPK2ALDH1A1MAPK14 | |
| SCHEMBL19908940 | 0.89 | GRM5 (0.39) | CHEK1FLT3MAPK14CSNK1A1CSNK1D | |
| SCHEMBL19913138 | 0.89 | MAPK14 (0.36) | FLT3ALDH1A1MAPK14CSNK1A1CSNK1D | |
| SCHEMBL19909478 | 0.88 | FLT3 (0.41) | CHEK1FLT3MAPK14CSNK1A1CSNK1D | |
| SCHEMBL19909067 | 0.88 | MAPKAPK2 (0.39) | CHEK1FLT3MAPKAPK2ALDH1A1CYP2A6 | |
| SCHEMBL19913158 | 0.87 | MAPK14 (0.45) | CHEK1FLT3ALDH1A1MAPK14CYP11B2 | |
| SCHEMBL25658975 | 0.87 | PDE1C (0.41) | CHEK1MAPKAPK2ALDH1A1CYP2A6KDM1A | |
| SCHEMBL19913152 | 0.87 | IMPDH2 (0.39) | FLT3MAPK14CSNK1A1CSNK1DCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287451-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |