SCHEMBL19913161

SCHEMBL19913161

Cc1ccc(-c2ccc3c4ccc(-c5ccc(C)cc5)cc4n(-c4cc(C#N)cc(-n5c6cc(-c7ccc(C)cc7)ccc6c6ccc(-c7ccc(C)cc7)cc65)c4-c4ccncc4)c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.40
CHEK1 O14757 3/20 0.38
MAPKAPK2 P49137 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
MAPK14 Q16539 2/20 0.35
CSNK1A1 P48729 1/20 0.35
CSNK1D P48730 1/20 0.35
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
METAP2 P50579 3/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909508 0.98 CHEK1 (0.42) FLT3CHEK1MAPKAPK2PIK3CDPIK3CA
SCHEMBL19908939 0.94 MAPK14 (0.40) FLT3CHEK1MAPKAPK2PIK3CDPIK3CA
SCHEMBL19908940 0.92 GRM5 (0.39) FLT3CHEK1MAPK14CSNK1A1CSNK1D
SCHEMBL19913138 0.91 MAPK14 (0.36) FLT3MAPK14CSNK1A1CSNK1DLMNA
SCHEMBL19919611 0.91 FLT3 (0.42) FLT3CHEK1MAPK14CSNK1A1CSNK1D
SCHEMBL19909067 0.90 MAPKAPK2 (0.39) FLT3CHEK1MAPKAPK2PIK3CDPIK3CA
SCHEMBL19913158 0.90 MAPK14 (0.45) FLT3CHEK1MAPK14ALDH1A1KDM4E
SCHEMBL19913152 0.89 IMPDH2 (0.39) FLT3PIK3CAMAPK14CSNK1A1CSNK1D
SCHEMBL19909119 0.89 FLT3 (0.37) FLT3CHEK1MAPK14CSNK1A1CSNK1D
SCHEMBL21414101 0.89 ALDH1A1 (0.37) CHEK1MAPKAPK2ALDH1A1KDM4EGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 FLT3 2571/4885CHEK1 3673/4885MAPKAPK2 3739/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 FLT3 2571/4885CHEK1 3673/4885MAPKAPK2 3739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.