Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2612438 | 0.93 | GAA (0.50) | GAAAPPTDP1ALOX5MGLL | |
| SCHEMBL824539 | 0.81 | GAA (0.57) | GAAAPPTDP1ALDH1A1 | |
| SCHEMBL15415622 | 0.78 | GAA (0.36) | GAAAPPTDP1MGLLALDH1A1 | |
| SCHEMBL16299167 | 0.74 | GAA (0.49) | GAAAPPTDP1ALOX5 | |
| SCHEMBL15430188 | 0.74 | ALOX5 (0.40) | GAAAPPTDP1ALOX5NAAA | |
| SCHEMBL19909643 | 0.74 | ALOX5 (0.36) | GAAAPPTDP1ALOX5ALDH1A1 | |
| SCHEMBL10479277 | 0.72 | GAA (0.59) | GAATDP1ALDH1A1 | |
| SCHEMBL2612461 | 0.72 | GAA (0.66) | GAAALDH1A1 | |
| SCHEMBL10372823 | 0.71 | GAA (0.62) | GAAALDH1A1 | |
| SCHEMBL19894685 | 0.71 | ALOX5 (0.37) | GAAAPPTDP1ALOX5NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872496-B1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL]DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | BASF SE (DE) | 2018-02-28 | — | — | EP | disclosed |