SCHEMBL2612438

SCHEMBL2612438

O=C(CCc1ccc2c(c1)C(c1ccccc1)C(=O)O2)OCCCCCCCCCCOC(=O)CCc1ccc2c(c1)C(c1ccccc1)C(=O)O2

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.50
APP P05067 2/20 0.47
TDP1 Q9NUW8 1/20 0.46
ALOX5 P09917 1/20 0.40
MGLL Q99685 2/20 0.37
FAAH O00519 1/20 0.37
ALDH1A1 P00352 1/20 0.37
NAAA Q02083 1/20 0.36
P2RY10 O00398 1/20 0.36
FFAR1 O14842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909640 0.93 GAA (0.44) GAAAPPTDP1ALOX5MGLL
SCHEMBL824539 0.87 GAA (0.57) GAAAPPTDP1ALDH1A1
SCHEMBL15415622 0.84 GAA (0.36) GAAAPPTDP1MGLLALDH1A1
SCHEMBL844100 0.80 GAA (0.59) GAAAPPTDP1ALOX5ALDH1A1
SCHEMBL16299167 0.80 GAA (0.49) GAAAPPTDP1ALOX5FFAR1
SCHEMBL15430188 0.80 ALOX5 (0.40) GAAAPPTDP1ALOX5NAAA
SCHEMBL10479277 0.78 GAA (0.59) GAATDP1ALDH1A1
SCHEMBL2612461 0.77 GAA (0.66) GAAALDH1A1
SCHEMBL10372823 0.77 GAA (0.62) GAAALDH1A1
SCHEMBL19894685 0.77 ALOX5 (0.37) GAAAPPTDP1ALOX5NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2872496-B1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL]DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2018-02-28 EP disclosed
EP-2872496-B1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL]DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2018-02-28 EP disclosed
US-9328218-B2 Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material BASF SE (DE) 2016-05-03 US disclosed
US-9328218-B2 Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material BASF SE (DE) 2016-05-03 US disclosed
US-9328218-B2 Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material BASF SE (DE) 2016-05-03 US disclosed
US-20150191581-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2015-07-09 US disclosed
US-20150191581-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2015-07-09 US disclosed
US-20150191581-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2015-07-09 US disclosed
WO-2014009361-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2014-01-16 WO disclosed
US-20120298007-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2012-11-29 US disclosed
US-20090246416-A1 OPTICAL FILM, METHOD OF MANUFACTURING THE SAME, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2009-10-01 US disclosed
US-20090246416-A1 OPTICAL FILM, METHOD OF MANUFACTURING THE SAME, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2009-10-01 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
EP-2006716-A1 FILM FOR DISPLAY, POLARIZING PLATE AND METHOD FOR PRODUCING THE SAME, AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2008-12-24 EP disclosed
US-20080122128-A1 Method for producing optical film KONICA MINOLTA OPTO, INC. (JP) 2008-05-29 US disclosed
US-20080122128-A1 Method for producing optical film KONICA MINOLTA OPTO, INC. (JP) 2008-05-29 US disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191581-A1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL H1-0, PCBP1, HEATR1 GAA 624/4885APP 2651/4885TDP1 1311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.