Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | CKS1B | P61024 | 2/20 | 0.44 |
| ▸ | SKP1 | P63208 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075325 | 0.87 | CKS1B (0.47) | GPR119CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL16075324 | 0.86 | JAK2 (0.48) | GPR119CKS1BSKP1SKP2 | |
| SCHEMBL16075326 | 0.85 | ALDH1A1 (0.50) | CKS1BSKP1SKP2ALDH1A1MAPT | |
| SCHEMBL1146996 | 0.79 | CKS1B (0.46) | GPR119CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL16075323 | 0.79 | CKS1B (0.47) | GPR119CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL16075313 | 0.78 | CKS1B (0.46) | CKS1BSKP1SKP2ALDH1A1MAPT | |
| SCHEMBL3100957 | 0.78 | KMT2A (0.64) | GPR119CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL16075342 | 0.77 | CKS1B (0.46) | GPR119CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL16075322 | 0.77 | SMN1; SMN2 (0.47) | CKS1BSKP1SKP2ALDH1A1MAPT | |
| SCHEMBL18939632 | 0.77 | CKS1B (0.46) | GPR119CKS1BSKP1SKP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970163-B1 | 5-THIAZOLECARBOXAMIDE DERVATIVES AND THEIR USE AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-02-28 | — | — | EP | disclosed |