Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146996 | 0.87 | CKS1B (0.46) | CKS1BSKP1SKP2PKMAR | |
| SCHEMBL3767883 | 0.87 | CKS1B (0.61) | CKS1BSKP1SKP2ARMAPT | |
| SCHEMBL16075325 | 0.82 | CKS1B (0.47) | CKS1BSKP1SKP2PKMSMN1; SMN2 | |
| SCHEMBL19909690 | 0.77 | GPR119 (0.46) | CKS1BSKP1SKP2SMN1; SMN2MAPT | |
| SCHEMBL1146899 | 0.77 | CKS1B (0.50) | CKS1BSKP1SKP2ARSMN1; SMN2 | |
| SCHEMBL16075324 | 0.76 | JAK2 (0.48) | CKS1BSKP1SKP2GPR119 | |
| SCHEMBL20767954 | 0.76 | NPC1 (0.55) | SMN1; SMN2MAPTLMNAMEN1CYP2C19 | |
| SCHEMBL3100957 | 0.76 | KMT2A (0.64) | CKS1BSKP1SKP2SMN1; SMN2MAPT | |
| SCHEMBL6132325 | 0.76 | MAPT (0.58) | PKMSMN1; SMN2MAPTLMNAGPR119 | |
| SCHEMBL16075326 | 0.76 | ALDH1A1 (0.50) | CKS1BSKP1SKP2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166538-A1 | PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166538-A1 | PROTEASE INHIBITORS | MMP8, CTSK, CTSS | CKS1B 305/4885SKP1 839/4885SKP2 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.