Cyclohexane

Cyclohexane

SCHEMBL1991228

C1CCCCC1.CCCCC(CC(C)(OOC(C)(C)C)OOC(C)(C)C)C(=O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.49
MAPK1 P28482 1/20 0.49
SLC1A2 P43004 2/20 0.42
SLC1A1 P43005 2/20 0.42
SLC1A3 P43003 1/20 0.42
GRIK1 P39086 2/20 0.38
GRIK2 Q13002 2/20 0.38
PPARG P37231 4/20 0.38
CA1 P00915 4/20 0.38
CHRM1 P11229 1/20 0.37
AKR1A1 P14550 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
ADRA1A P35348 1/20 0.37
HRH1 P35367 1/20 0.37
DRD3 P35462 1/20 0.37
SLC6A3 Q01959 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22530 0.95 CA2 (0.53) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL8429202 0.91 CA2 (0.49) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL21456967 0.88 CA2 (0.39) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL2335987 0.88 CA2 (0.39) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL1883197 0.83 CA2 (0.50) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL6763270 0.82 CA2 (0.46) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL8387652 0.81 CA2 (0.40) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL31291504 0.81 PTGES (0.40) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL6243508 0.80 CA2 (0.55) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL9657821 0.80 CA2 (0.47) CA2MAPK1SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516703-B1 ELASTIC FIBER CONTAINING AN ANTI-TACK ADDITIVE INVISTA TECH SARL (CH) 2020-04-29 EP disclosed
US-8431065-B2 Polyolefin-based crosslinked articles EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-30 US disclosed
US-20120220682-A1 Polyolefin-Based Crosslinked Articles EXXONMOBIL CHEMICAL PATENTS INC. 2012-08-30 US disclosed
US-20110151233-A1 FABRIC INCLUDING POLYOLEFIN ELASTIC FIBER INVISTA NORTH AMERICA S.A.R.L. (US) 2011-06-23 US disclosed
US-7964672-B2 High strength thermoplastic elastomers with high filler loading EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-06-21 US disclosed
US-7829623-B2 Thermoplastic vulcanizates having improved fabricability EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-11-09 US disclosed
EP-1655332-B1 Thermoplastic vulcanizates having improved fabricability ADVANCED ELASTOMER SYSTEMS (US) 2008-12-31 EP disclosed
US-7413784-B2 Thermoplastic vulcanizates for potable water applications ADVANCED ELASTOMER SYSTEMS, L.P. (US) 2008-08-19 US disclosed
EP-1619218-B1 Thermoplastic vulcanizates with enhanced cooling and articles made therefrom ADVANCED ELASTOMER SYSTEMS (US) 2008-05-28 EP disclosed
US-20070292648-A1 Thermoplastic vulcanizates for potable water applications EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-20060100347-A1 Thermoplastic vulcanizates having improved fabricability CELANESE INTERNATIONAL CORPORATION 2006-05-11 US disclosed
US-20060100377-A1 High strength thermoplastic elastomers with high filler loading EXXONMOBIL CHEMICAL PATENTS INC. 2006-05-11 US disclosed
EP-1655332-A1 Thermoplastic vulcanizates having improved fabricability Advanced Elastomer Systems, L.P. (US) 2006-05-10 EP disclosed
EP-1655331-A1 High strength thermoplastic elastomers with high filler loading Advanced Elastomer Systems, L.P. (US) 2006-05-10 EP disclosed
EP-1619218-A1 Thermoplastic vulcanizates with enhanced cooling and articles made therefrom Advanced Elastomer Systems, L.P. (US) 2006-01-25 EP disclosed
US-20060014903-A1 Thermoplastic vulcanizates with enhanced cooling and articles made therefrom ADVANCED ELASTOMER SYSTEMS, L.P. 2006-01-19 US disclosed
US-20040127643-A1 Thermoplastic elastomers having improved adhesive proterties ADVANCED ELASTOMER SYSTEMS, L.P. 2004-07-01 US disclosed
US-6503985-B1 Vulcanizing rubber within mixture that includes 15-90 percent by weight rubber and 10-85 percent by weight long-chain branched thermoplastic alpha-olefin polymer or copolyumer with olefin diene ADVANCED ELASTOMER SYSTEMS, L.P. 2003-01-07 US disclosed
US-6451915-B1 DYNAMICALLY VULCANIZING A RUBBER WITHIN A BLEND THAT INCLUDES A THERMOPLASTIC RESIN, AND A POLYMERIC PROCESSING ADDITIVE COMPRISING A POLYOLEFIN OR DIENE-MODIFIED POLYOLEFIN OF HIGH MELT FLOW INDEX ADVANCED ELASTOMER SYSTEMS, L.P. 2002-09-17 US disclosed
US-6433090-B1 CURABLE RUBBER BLEND ADVANCED ELASTOMER SYSTEMS, L.P. 2002-08-13 US disclosed