SCHEMBL19913149

SCHEMBL19913149

Cc1ccc2c(c1)c1ccccc1n2-c1cc(C#N)cc(-n2c3ccccc3c3cc(C(F)(F)F)ccc32)c1-c1ccncc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.36
GPBAR1 Q8TDU6 1/20 0.35
MAPK14 Q16539 5/20 0.34
PTGDR2 Q9Y5Y4 2/20 0.33
HRH1 P35367 2/20 0.33
HTR6 P50406 2/20 0.33
ELANE P08246 1/20 0.33
MAT2A P31153 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP3A5 P20815 1/20 0.32
GRM5 P41594 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PIK3CG P48736 1/20 0.32
CSNK1A1 P48729 1/20 0.31
CSNK1D P48730 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913157 0.95 KIF11 (0.37) KIF11GPBAR1MAPK14PTGDR2HRH1
SCHEMBL19908948 0.94 KIF11 (0.37) KIF11GPBAR1MAPK14HRH1HTR6
SCHEMBL19913146 0.92 KIF11 (0.40) KIF11GPBAR1MAPK14PTGDR2ELANE
SCHEMBL19913139 0.91 MAPK14 (0.37) MAPK14ELANEABCG2CSNK1A1CSNK1D
SCHEMBL19909329 0.89 KIF11 (0.40) KIF11GPBAR1MAPK14HRH1HTR6
SCHEMBL22170411 0.89 S1PR1 (0.35) KIF11GPBAR1MAPK14ELANE
SCHEMBL19908947 0.88 KIF11 (0.42) KIF11MAPK14MAT2AABCG2CYP3A4
SCHEMBL19912479 0.87 KIF11 (0.36) KIF11PTGDR2HRH1HTR6ELANE
SCHEMBL19913151 0.87 KIF11 (0.35) KIF11MAPK14PTGDR2ELANEMAT2A
SCHEMBL19913135 0.87 KIF11 (0.37) KIF11MAPK14CSNK1A1CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed