Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.92 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.92 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27439894 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL434375 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL123904 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL29555335 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL1195618 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Ammonia Solution, Strong SCHEMBL9146631 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL612491 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL809368 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL5241027 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL809433 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1068 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4190769-B1 | APPLICATION OF POLYDENTATE PHOSPHITE LIGAND IN CATALYTIC SYNTHESIS OF ADIPONITRILE | ZHEJIANG NHU CO LTD (CN) | 2026-02-11 | — | — | EP | claimed |
| US-12331007-B2 | Use of a multidentate phosphite ligand in the catalytic synthesis of adiponitrile | ZHEJIANG NHU CO., LTD. (CN) | 2025-06-17 | — | — | US | claimed |
| CN-116947865-B | Synthesis method of risperidone intermediate and Li Sipu-blue intermediate | 扬州联澳生物医药有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120081782-A | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethylpyridine | 天津均凯农业科技有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-118955233-B | Synthesis method of monosubstituted bicyclo [1.1.1] pentane (BCP) | 康龙化成手性医药技术(宁波)有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119912652-A | Ionic liquid polymer catalyst and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2025-05-02 | — | — | CN | claimed |
| US-12280364-B2 | Complex compound and method for manufacturing the same | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2025-04-22 | — | — | US | claimed |
| CN-119798212-A | Preparation method of lubabaril intermediate 2-thiophenol | 浙江永太科技股份有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-118955233-A | Synthesis method of monosubstituted bicyclo [1.1.1] pentane (BCP) | 康龙化成手性医药技术(宁波)有限公司 | 2024-11-15 | — | — | CN | claimed |
| US-20240336560-A1 | Use of a Multidentate Phosphite Ligand in the Catalytic Synthesis of Adiponitrile | ZHEJIANG NHU CO., LTD. (CN) | 2024-10-10 | — | — | US | claimed |
| CN-1429767-A | Preparation method of nano carbon material | CANON KK (JP) | 2003-07-16 | — | — | CN | claimed |
| CN-1396194-A | Process for preparing biphenyl polyimide | CHANGCHUN APPLIED CHEMISTRY (CN) | 2003-02-12 | — | — | CN | claimed |
| CN-1390644-A | Catalysis system f nitrogen-phosphinonickel matches and its preparing process and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-15 | — | — | CN | claimed |
| CN-1081627-C | Process for synthesizing benzoic acids | ROHM & HAAS (US) | 2002-03-27 | — | — | CN | claimed |
| CN-1196055-A | 2-[[2-(2-hydroxyethyl) amino] ethyl]-5-[[2-methylamino) ethyl] amino] [4,3-gh] isoquinolin-6(2H)-one as antitumor agent | BOEHRINGER MANNHEIM ITALIA (IT) | 1998-10-14 | — | — | CN | claimed |
| CN-1188107-A | Process for synthesizing benzoic acids | ROHM & HAAS (US) | 1998-07-22 | — | — | CN | claimed |
| CN-1149293-A | Process for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid | SYNTEX INC (US) | 1997-05-07 | — | — | CN | claimed |
| CN-1108659-A | Trifluoroisopropenyl zinc reagent and its derivate application | SHANGHAI INST ORGANIC CHEM (CN) | 1995-09-20 | — | — | CN | claimed |
| CN-1059516-A | The preparation method of biphenylcarbonitriles | ICI LTD (GB) | 1992-03-18 | — | — | CN | claimed |
| CN-1051911-A | Trifluoroisopropenyl zinc reagent and derivative, preparation and application thereof | SHANGHAI ORGANIC CHEMESTRY INS (CN) | 1991-06-05 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12331007-B2 | Use of a multidentate phosphite ligand in the catalytic synthesis of adiponitrile | FABP4, LIPE, FASN | TDP1 4423/4885CYP3A4 1130/4885ESR1 1998/4885 |
| US-20240336560-A1 | Use of a Multidentate Phosphite Ligand in the Catalytic Synthesis of Adiponitrile | FABP4, LIPE, FASN | TDP1 4423/4885CYP3A4 1130/4885ESR1 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.