Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914213 | 0.84 | ALDH1A1 (0.51) | TDP1KMT2ASLC6A2SLC6A3RAF1 | |
| SCHEMBL19914227 | 0.82 | ALDH1A1 (0.46) | TDP1KMT2ASLC6A2SLC6A3RAF1 | |
| SCHEMBL19914214 | 0.81 | RAF1 (0.57) | TDP1KMT2ASLC6A2SLC6A3RAF1 | |
| SCHEMBL19914219 | 0.79 | TDP1 (0.48) | TDP1KMT2ASLC6A2SLC6A3RAF1 | |
| SCHEMBL19914215 | 0.77 | POLB (0.51) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL19914220 | 0.77 | EGLN1 (0.44) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL19914284 | 0.75 | TDP1 (0.47) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL25713483 | 0.75 | TDP1 (0.64) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL19914280 | 0.74 | JMJD6 (0.46) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL19779307 | 0.73 | TDP1 (0.66) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018037223-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2018-03-01 | — | — | WO | disclosed |