Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914214 | 0.81 | RAF1 (0.57) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL19914218 | 0.79 | TDP1 (0.48) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL19914221 | 0.76 | POLB (0.47) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL25825736 | 0.76 | TDP1 (0.57) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL28566903 | 0.75 | LMNA (0.57) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL20305861 | 0.75 | TDP1 (0.64) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL8626786 | 0.75 | MAOB (0.47) | KMT2ALMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20830744 | 0.74 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL6741897 | 0.73 | MGAM (0.60) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL18607178 | 0.72 | TSHR (0.54) | TDP1KMT2ASLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018037223-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2018-03-01 | — | — | WO | disclosed |