Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 2/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19915018 | 0.77 | ELANE (0.37) | ELANESIGMAR1CTSGPRTN3SLC6A2 | |
| SCHEMBL27895707 | 0.67 | ELANE (0.43) | ELANESIGMAR1CTSGPRTN3F2 | |
| (Chloromethyl)Benzene SCHEMBL4637240 | 0.66 | TP53 (0.50) | SIGMAR1SLC6A2TAAR1LMNA | |
| (Chloromethyl)Benzene SCHEMBL2146684 | 0.64 | SLC6A2 (0.44) | SLC6A2TAAR1CYP1A2POLBLMNA | |
| SCHEMBL9838379 | 0.64 | ALDH1A1 (0.42) | ELANEGSK3AGSK3BMGLLSIGMAR1 | |
| SCHEMBL24689745 | 0.61 | ELANE (0.48) | ELANESIGMAR1CTSGPRTN3F2 | |
| SCHEMBL17700194 | 0.61 | GAA (0.53) | ELANESIGMAR1CTSGPRTN3F2 | |
| SCHEMBL15285550 | 0.61 | TAAR1 (0.41) | SIGMAR1SLC6A2TAAR1CYP1A2CYP2C19 | |
| SCHEMBL3698481 | 0.61 | TAAR1 (0.52) | SLC6A2TAAR1CYP1A2CYP2C19LMNA | |
| SCHEMBL8002017 | 0.61 | SLC6A2 (0.58) | SLC6A2TAAR1CYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | AHR, TYR, CYP1A1 | ELANE 2444/4885GSK3A 2094/4885GSK3B 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.