Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18464729 | 0.84 | CHEK1 (0.37) | KDM4EGPR3EGLN2ATMCYP11B1 | |
| SCHEMBL18464722 | 0.83 | EGFR (0.40) | ATMCYP11B1CYP11B2 | |
| SCHEMBL3971747 | 0.76 | KDM4E (0.42) | KDM4EGPR3ATML3MBTL1CYP11B1 | |
| SCHEMBL18425832 | 0.76 | DHODH (0.40) | KDM4EGPR3L3MBTL1 | |
| SCHEMBL18464716 | 0.75 | CYP1A2 (0.43) | KDM4EGPR3L3MBTL1 | |
| SCHEMBL18464723 | 0.74 | TDP1 (0.48) | KDM4EGPR3L3MBTL1 | |
| SCHEMBL18464720 | 0.73 | CYP11B1 (0.37) | KDM4EGPR3ALOX5APFEN1L3MBTL1 | |
| SCHEMBL18464633 | 0.72 | GPR84 (0.39) | KDM4EGPR3 | |
| SCHEMBL18464728 | 0.72 | TACR1 (0.39) | L3MBTL1 | |
| SCHEMBL18425748 | 0.71 | PIK3CD (0.37) | KDM4EGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018038667-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2018-03-01 | — | — | WO | disclosed |