Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21057386 | 0.74 | PDE5A (0.46) | ADORA2AADORA2BADORA3ADORA1TLR7 | |
| SCHEMBL21159333 | 0.73 | PDE8B (0.43) | ADORA2AADORA2BADORA1 | |
| SCHEMBL4298079 | 0.70 | CDK1 (0.57) | ADORA2AADORA2BADORA3ADORA1MEN1 | |
| SCHEMBL21159423 | 0.69 | ABCB1 (0.33) | — | |
| SCHEMBL21159424 | 0.67 | — | — | |
| SCHEMBL21159259 | 0.67 | TLR7 (0.36) | TLR7 | |
| SCHEMBL26348959 | 0.64 | AHCY (0.44) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL19539500 | 0.63 | TLR7 (0.56) | ADORA2AADORA1TLR7 | |
| SCHEMBL10383664 | 0.62 | KMT2A (0.36) | ADORA2AADORA2BADORA3ADORA1TLR7 | |
| SCHEMBL7210234 | 0.62 | PDE4A (0.60) | ADORA2AADORA2BADORA1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |
| WO-2018038265-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2018-03-01 | — | — | WO | disclosed |