Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388765 | 0.68 | CDK1 (0.57) | TLR7FBP1CA12CA2CA9 | |
| SCHEMBL7753780 | 0.65 | LMNA (0.52) | CA12CA2CA9 | |
| SCHEMBL24773616 | 0.64 | LMNA (0.43) | TLR7CA12CA2CA9 | |
| SCHEMBL14767779 | 0.63 | FBP1 (0.35) | FBP1 | |
| SCHEMBL30730952 | 0.63 | TLR7 (0.32) | TLR7FBP1CA12CA2CA9 | |
| SCHEMBL18067288 | 0.62 | LMNA (0.35) | TLR7CA12CA2CA9 | |
| SCHEMBL24701697 | 0.61 | PI4KA (0.47) | TLR7CA12CA2CA9 | |
| SCHEMBL29487215 | 0.61 | PI4KA (0.47) | TLR7CA12CA2CA9 | |
| SCHEMBL11880705 | 0.61 | LMNA (0.38) | TLR7CA12CA2CA9 | |
| SCHEMBL10514950 | 0.61 | LMNA (0.38) | TLR7CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |